Evaluation of antioxidant and anticancer activities of families Lamiaceae and Caryophyllaceae
DOI:
https://doi.org/10.18372/2306-6407.1.13762Keywords:
extraction, bioactive compounds, antioxidants, anticancer activity, ascorbic acid, phenols, WISH cell lineAbstract
Article presents the results of experimental investigation of antioxidant and anticarcinogenic activity of plant extracts of families Lamiaceae and Caryophyllaceae. Selected species are: Salvia officinalis, Origanum vulgare, Melissa officinalis, Stellaria media. The determination of ascorbic acid content and total phenols content is carried out. Cytotoxic activity of plant extracts is evaluated using WISH cell lines. The following methodologies are concidered: spectrophotometry; photoelectric colorimetry; microscopic method based on inhibition and quantification of cancer cell lines.References
Natural Antioxidants in Foods and Medicinal Plants: Extraction, Assessment and Resources / [Dong-Ping Xu, Ya Li, Xiao Meng et. al] // International Journal of Molecular Sciences. – 2017. – Vol. 18 (1). – P. 96–128.
Taskin T. Antioxidant activity of Silene alba subsp. divaricata and Stellaria media subsp. media from Caryophyllaceae / T. Taskin, L. Bitis // ScopeMed. – 2013. – Vol. 3(1). – P. 1–5.
Phytochemical Screening, Anticancer and Antioxidant Activities of Origanum vulgare L. / [Serkan Kolda¸ Ibrahim Demirtas, Tevfik Ozen et. al] // Journal of the Science of Food and Agriculture. – 2015. – Vol. 95 (4). – P. 786–798.
Sepide Miraj Melissa officinalis L: A Review Study With an Antioxidant Prospective / Sepide Miraj, Rafieian-Kopaei, Sara Kiani // Journal of Evidence-Based Complementary and Alternative Medicine. – 2017. – Vol. 23 (3). – P. 385–394.
WISH cell line: from the antiviral system to a novel reporter gene assay to test the potency of human IFN-α and IFN-β / [L. Bürgi Mde, C. Prieto, M. Etcheverrigaray et. al] // J. Immunol. Methods. – 2012. – Vol. 381(1–2). – P. 70–4.
Spectrophotometric analysis of total ascorbic acid content in various fruits and vegetables / A. Kapur, A. Haskovic, L. Klepo // Bulettin of the Chemists and Technologists of Bosnia and Herzegovina. – 2012. – Vol. 38. – P. 39–42.
Salvia officinalis of different origins. Antioxidant activity, phenolic and flavonoid content of extracts / S. Duletic, A. Alimpic, D. Pavlovic // Agro Food Industry Hi Tech. – 2016. – Vol. 27 (1). – P. 52–55.