Дослідження типових конформацій протеїнтирозинфосфатази 1B за допомогою докінгу

Volodymyr Tanin, Vsevolod Tanchuk

Анотація


За допомогою докінгу відомих інгібіторів досліджено типові конформації протеїнтирозинфосфатази 1B.Найкращої конформації не виявлено, хоча для кожного інгібітора існує найбільш відповідна конформація.

Ключові слова


докінг; кластеризація; конформації; протеїнтирозинфосфатази 1B; сайти зв’язування; структурна подібність

Посилання


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