LYMPHOCYTIC CHALONES IS A NEW CLASS OF NATURAL ANTIOXIDANTS
DOI:
https://doi.org/10.18372/2306-1472.58.6697Keywords:
antioxidants, free radical reactions, immunological reactions, lipid peroxidation, lymphocytic chalonesAbstract
The analysis of biological properties of lymphocytic chalones, regulators of cell proliferation, indicates the prospect of the creation of these new antioxidant preparations for the correction and normalization of immunological reactions in current adverse conditions of environment.References
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Baraboi, V.A. The role of peroxidation in the mechanism of stress. Physiolog Journal. 1989. N 5. P. 67–72 (in Russian).
Bullough, W.S. Chalone control mecha¬nisms. Life sci. 1975. Vol.16, N 3. P. 323–330.
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Burlakova, E.B.; Khokhlov, A.P. Changes in the structure and composition of lipid phases of biological membranes under the influence of antioxidants. Effect of the transmission of data signal at the cellular level. Biological Membranes. 1985. Vol. 2, N 6. P. 557–563 (in Russian).
Garcia-Giralt/ E.; Lenfant, M.; Privat de Garilhe, M.; Mayadoux, E.; Motta R. Purification of immunosuppressive factor extracted from bovine spleen (Lymphoid chalone). Biological activity. Cell. Tissue Kinet. 1978. Vol.11,N 5. P. 465–476.
Garkava, K.G. Effect of lymphoid chalones on the immune response: Abstract of disertation... Candidate of Biological Sciences. Kyiv. 1983. 18 p. (in Russian).
Garkava, K.G. The composition of the lipid matrix of the lymphocyte membranes after the action of G1 i G2 — lymphocyte chalones under the use of exogenous lymphocytic chalones during the immune response. Biopol. and Cell. 1998. Vol. 14, N 5. P. 410–413 (in Ukrainian).
Garkava, K.G. The role of lymphocyte chalones in the implementation of immune homeostasis. Abstract of disertation... Dr. of Biological Sciences. Kyiv. 2001. 36 p. (in Ukrainian).
Garkava, K.G.; Afonina, G.B.; Zadorina, O.V.; Bryuzhina, T.S. Influence of lymphocytic chalones on the functional activity of lymphocytes in antioxidant deficiency and correction of it with vitamin E. Physiology Journal. 1995. N 5–6. P. 27–32 (in Ukrainian).
Garkava, K.G.; Oleinik, S.O.; Zadorin O.V.; Mikhailova, I.S. Influence of lymphocytic chalone on metabolic processes in the lymphocytes in the immune response. Biopol. and Cell. 2000. Vol.16, N 4. P. 297–300 (in Ukrainian).
Garkava, K.G.; Yatsenko, V.P.; Dan, I.V.; Gorchakova, N.A.; Bordonos, V.G.; Bryuzhina, T.S. Biological effects of thymic chalones. Medicines. 1997. N 2. P. 38–42 (in Ukrainian).
Ketlynskii, S.A. Chalones as factors in tissue homeostasis. Archive of Anatomy, hystology and embryology. 1980. Vol.78. Issue 1. P. 29–43 (in Russian).
Kiger, N.; Florentin, I.; Mathe, G. Ingibition of graft-versus host reaction by preincubation of the graft with a thymic extract (lymphocyte chalone). Ransplantation. 1973. Vol. 16, N 5. P. 393–397.
Lukashova, R.G.; Malyzhev, V.A.; Baraboi, V.A.; Chebotarev, V.F. Influence of thymic hormones on activation of lipid peroxidation in rat lymphoid organs during development of the humoral immune response. Proceedings of the AN USSR. Ser. B. 1989. N 9. P. 63–67 (in Russian).
Lyashenko, V.A.; Molotkovskaya, I.M. Lipids of lymphocyte cell membrane and their alteration in the immunological activation. Results of Science and technology. Moscow, VYNYTY. Immunology. 1988. P. 22–42 (in Russian).
Mathe, G. Lymphocyte inhibitors fulfilling the definition of chalones and immunosupression. Eur. J. Clin. Biological Res. 1972. Vol. 17, N 6. P. 548–551.
Morgounov, I.N.; Garkava, K.G.; Bordonos, V.G. Influence of lymphocytic chalone on secondary immune response upon immunization with bacterial antigens. Microbe Journal. 1980. N 42. P. 605–608 (in Russian).
Neustroev, G.V. The role of chalones in the regulation of cell proliferative activity of the bone marrow, salivary glands and thymus. Abstract of dissertation ... Dr. Medical Science. Moscow. 1982. 46 p. (in Russian).
Pershin, S.B.; Konchugova, T.V. Stress and Immunity. Moscow, Press. 1996. 160 p. (in Russian).
Romanov, J.A.; Ketlinsky, S.A.; Antokhin, A.I.; Okulov, V.B. Chalones and the regulation of cell division. Moscow, Medicine. 1984. 207 p. (in Russian).
Tarusov, B.N. Free radical chain reactions in the lipids of biological systems. Free radical oxidation of lipids in norm and pathology. Moscow, Nauka, 1976. P. 22–24 (in Russian).
Vladimirov, J.A.; Archakov, A.I. Lipid peroxidation in biological membranes. Moscow, Nauka. 1972. 252 p. (in Russian).
Zenkov, N.K.; Lankin, V.Z.; Menshikov, E.B. Oxidative stress. Moscow, Nauka. 2001. 342 p. (in Russian).
Baraboi, V.A. The role of peroxidation in the mechanism of stress. Physiolog Journal. 1989. N 5. P. 67–72 (in Russian).
Bullough, W.S. Chalone control mecha¬nisms. Life sci. 1975. Vol.16, N 3. P. 323–330.
Burlakova, E.B. The role of lipids in the information transfer in cell. Biochemistry of lipids and their role in the substance exchange. Moscow, Science. 1981. P. 23–34 (in Russian).
Burlakova, E.B.; Khokhlov, A.P. Changes in the structure and composition of lipid phases of biological membranes under the influence of antioxidants. Effect of the transmission of data signal at the cellular level. Biological Membranes. 1985. Vol. 2, N 6. P. 557–563 (in Russian).
Garcia-Giralt/ E.; Lenfant, M.; Privat de Garilhe, M.; Mayadoux, E.; Motta R. Purification of immunosuppressive factor extracted from bovine spleen (Lymphoid chalone). Biological activity. Cell. Tissue Kinet. 1978. Vol.11,N 5. P. 465–476.
Garkava, K.G. Effect of lymphoid chalones on the immune response: Abstract of disertation... Candidate of Biological Sciences. Kyiv. 1983. 18 p. (in Russian).
Garkava, K.G. The composition of the lipid matrix of the lymphocyte membranes after the action of G1 i G2 — lymphocyte chalones under the use of exogenous lymphocytic chalones during the immune response. Biopol. and Cell. 1998. Vol. 14, N 5. P. 410–413 (in Ukrainian).
Garkava, K.G. The role of lymphocyte chalones in the implementation of immune homeostasis. Abstract of disertation... Dr. of Biological Sciences. Kyiv. 2001. 36 p. (in Ukrainian).
Garkava, K.G.; Afonina, G.B.; Zadorina, O.V.; Bryuzhina, T.S. Influence of lymphocytic chalones on the functional activity of lymphocytes in antioxidant deficiency and correction of it with vitamin E. Physiology Journal. 1995. N 5–6. P. 27–32 (in Ukrainian).
Garkava, K.G.; Oleinik, S.O.; Zadorin O.V.; Mikhailova, I.S. Influence of lymphocytic chalone on metabolic processes in the lymphocytes in the immune response. Biopol. and Cell. 2000. Vol.16, N 4. P. 297–300 (in Ukrainian).
Garkava, K.G.; Yatsenko, V.P.; Dan, I.V.; Gorchakova, N.A.; Bordonos, V.G.; Bryuzhina, T.S. Biological effects of thymic chalones. Medicines. 1997. N 2. P. 38–42 (in Ukrainian).
Ketlynskii, S.A. Chalones as factors in tissue homeostasis. Archive of Anatomy, hystology and embryology. 1980. Vol.78. Issue 1. P. 29–43 (in Russian).
Kiger, N.; Florentin, I.; Mathe, G. Ingibition of graft-versus host reaction by preincubation of the graft with a thymic extract (lymphocyte chalone). Ransplantation. 1973. Vol. 16, N 5. P. 393–397.
Lukashova, R.G.; Malyzhev, V.A.; Baraboi, V.A.; Chebotarev, V.F. Influence of thymic hormones on activation of lipid peroxidation in rat lymphoid organs during development of the humoral immune response. Proceedings of the AN USSR. Ser. B. 1989. N 9. P. 63–67 (in Russian).
Lyashenko, V.A.; Molotkovskaya, I.M. Lipids of lymphocyte cell membrane and their alteration in the immunological activation. Results of Science and technology. Moscow, VYNYTY. Immunology. 1988. P. 22–42 (in Russian).
Mathe, G. Lymphocyte inhibitors fulfilling the definition of chalones and immunosupression. Eur. J. Clin. Biological Res. 1972. Vol. 17, N 6. P. 548–551.
Morgounov, I.N.; Garkava, K.G.; Bordonos, V.G. Influence of lymphocytic chalone on secondary immune response upon immunization with bacterial antigens. Microbe Journal. 1980. N 42. P. 605–608 (in Russian).
Neustroev, G.V. The role of chalones in the regulation of cell proliferative activity of the bone marrow, salivary glands and thymus. Abstract of dissertation ... Dr. Medical Science. Moscow. 1982. 46 p. (in Russian).
Pershin, S.B.; Konchugova, T.V. Stress and Immunity. Moscow, Press. 1996. 160 p. (in Russian).
Romanov, J.A.; Ketlinsky, S.A.; Antokhin, A.I.; Okulov, V.B. Chalones and the regulation of cell division. Moscow, Medicine. 1984. 207 p. (in Russian).
Tarusov, B.N. Free radical chain reactions in the lipids of biological systems. Free radical oxidation of lipids in norm and pathology. Moscow, Nauka, 1976. P. 22–24 (in Russian).
Vladimirov, J.A.; Archakov, A.I. Lipid peroxidation in biological membranes. Moscow, Nauka. 1972. 252 p. (in Russian).
Zenkov, N.K.; Lankin, V.Z.; Menshikov, E.B. Oxidative stress. Moscow, Nauka. 2001. 342 p. (in Russian).
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Published
25-06-2014
How to Cite
Garkava, K. (2014). LYMPHOCYTIC CHALONES IS A NEW CLASS OF NATURAL ANTIOXIDANTS. Proceedings of National Aviation University, 58(1), 75–79. https://doi.org/10.18372/2306-1472.58.6697
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BIOTECHNOLOGY
