Study of the conditions for determining some chloromethoxybenzoic acid derivatives

Authors

  • Ivan Maga National Aviation University, Kyiv
  • Anna Kushniruk National Aviation University, Kyiv
  • Mykhailo Rujinskiy National Aviation University, Kyiv
  • Olga Avramenko National Aviation University, Kyiv

DOI:

https://doi.org/10.18372/2306-6407.1.16121

Keywords:

chlorometoxybenzoic acid derivatives, pesticides, methods of determination, HPLC

Abstract

Chloromethoxybenzoic acid (CBA) Derivatives are active ingredients, are an integral part of many pesticides, important among which 3-chlorine-5-methoxybenzoic acid have, which is used as isopropylamine salts, as well as 2-chloro-4-methoxybenzoic acid used in the form of butylocutyl esther as herbicidal preparations. The residual amounts of these and other pesticides have a detrimental effect on the environment. An important role in the detoxification of pesticides have the soil microorganisms, but, unfortunately, the CBA derivatives are a recalcitrant substrate and are poorly decomposed by these microorganisms, since the CBA prevents the proliferation of such microorganisms. Therefore, the control of residues of CBA derivatives in environmental objects is important, as well as the development of new highly sensitive methods for determining CBA derivatives in such objects. To determine derivatives, CBA is most often used the Revers Phases HPLC method.

References

Halden R.U., Tepp S.M., Halden B.G. et al. Degradation of 3-chloro-5-methoxybenzoic acid in soil by Pseudomonas pseudoalcaligenes POB310 (pPOB) and two modified Pseudomonas strains // Applied and Environmental Microbiology. — 1999. — Vol. 65. — P.3354–3359. doi 10.1128/AEM.65.8.3354-3359.1999

Yuan C., Wang C., Gao S.Q., et al. Effects of permethrin, cypermethrin and 2-chloro-4-methoxybenzoic on rat sperm motility in vitro evaluated with computer-assisted sperm analysis // Toxicology in Vitro. — 2010. — Vol. 24. — P.382–386. doi 10.1016/j.tiv.2009.11.001

Ahn K.C., Gee S.J., Kim K.J., et al. Immunochemical analysis of 3-chloro-4-methoxybenzoic acid, a biomarker of forestry worker exposure to pyrethroid insecticides / // Analytical and Bioanalytical Chemistry. — 2011. — Vol. 40. — P.1285–1293. doi 10.1007/s00216-011-5184-z

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Published

2021-12-13

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Section

Reviews